in accordance with current practice, a pregnancy test with a minimum sensitivity of 25 mME / ml should be performed in the first 3 days of the menstrual cycle: Prior to starting therapy. To exclude the possibility of pregnancy prior to the use of contraceptives and the andriol tc result of the initial date of a pregnancy test should be registered doctor. Patients with irregular menstrual periods while holding pregnancy test depends on the sexual activity, it should be carried out 3 weeks after unprotected intercourse. The physician should inform the patient about contraception.
A pregnancy test is carried out on the day of the appointment of the drug or 3 days prior to the patient visit. Professionals should record the test results. The drug can be assigned only to patients who receive effective contraception for at least 1 month before the start of therapy . During therapy:
The patient should visit the doctor every 28 days. The need monthly pregnancy testing is determined in accordance with local practice and the sexual activity prior to menstrual disorders. Where indicated, a pregnancy test is carried out in a visit a day or three days before the visit to the doctor, the test results must be registered. The end of therapy:
After 5 weeks after the end of therapy, a test to exclude pregnancy.
Recipe on andriol tc female, fertility, can only be issued for 30 days of treatment, the continuation of treatment requires a new prescription of a doctor medication. It is recommended to test for pregnancy, prescribing and obtaining medication to spend in one day.
The issuance of the in a pharmacy should be carried out only within 7 days from the date of the prescription.
To help physicians, pharmacists and patients to avoid the risk of exposure to the drug in the fruit company -Manufacturer created a “Programme of prevention of pregnancy”, aimed at warning about the teratogenicity of the drug and underscore absolutely mandatory use of reliable measures of contraception women of childbearing age. The program contains the following materials: for doctors: – a guide for the doctor on the appointment of the drug andriol tc women – a consent form for the patient – a form of accounting appointment of the drug to women for the patient: – an information leaflet for the patient – you need to know about contraception for the pharmacist: – a guide for pharmacist for the drug release Roaccutane ® . for complete information about the teratogenic risk and the strict adherence to measures to prevent pregnancy should be given to both men and women.
The available data suggest that in women the exposure of the drug delivered from the semen and seminal fluid of men taking , is not sufficient for the emergence of teratogenic effects .
Men should exclude the possibility of taking the drug by other persons, especially in women.
If despite the precautions taken during treatment with or within one month after the end of pregnancy yet occurred, there is a high risk of very severe fetal malformation (particularly on the part of the central nervous system, heart and major blood vessels). In addition, it increases the risk of miscarriage.
If pregnancy occurs, therapy with andriol tc is stopped. It should discuss the advisability of maintaining it with a doctor who specializes in Teratology.
Been documented severe congenital malformations of the fetus a person associated with the appointment of the drug , including hydrocephalus, microcephaly, developmental defects of the cerebellum, abnormalities of the outer ear (microtia, narrowing or absence of external ear canal), microphthalmia, cardiovascular anomalies (tetralogy of Fallot, transposition of the great vessels, partitions defects), the vices of persons development (cleft palate), the thymus gland, a pathology of the parathyroid glands.
As isotretinoin is highly lipophilic, it is very likely that he gets in breast milk. Because of the possible side effects of should not be administered to nursing mothers.