Post-marketing surveillance during the post-marketing surveillance with the use described cases of severe skin reactions such as erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis (see. Also “Special Instructions” section). When using andriol side effects , especially in patients who performed intense physical activity, reported serious cases of rhabdomyolysis, often lead to hospitalization. These phenomena in all cases were resolved successfully. Cases of renal failure have been reported.
Overdose In case of overdose there may be signs of hypervitaminosis A. In the first few hours of the overdose may require gastric lavage.
Interaction with other drugs because of the possible increase in hypervitaminosis symptoms And Avoid co-administration and vitamin A (retinol), as well as other oral retinoids. As tetracyclines may also cause increased intracranial pressure, their use in combination andriol testocaps contraindicated. Isotretinoin can weaken the effectiveness of progesterone drugs, so do not use contraceptives containing low doses of progesterone. Interactions with local keratolytic or exfoliative preparations for the treatment of acne is contraindicated due to the possible increase of local irritation.
Cautions Should appoint a doctor, preferably a dermatologist with experience in the use of systemic retinoids and knowledgeable about the risk of teratogenicity of the drug. Patients both female and male is necessary to issue a copy of the brochure with information for the patient. In order to prevent accidental exposure of the drug on the body of other people, in patients who receive or shortly before (1 month) gaveandriol side effects, you can not take blood transfusions. Recommended monitor liver function and liver enzymes before treatment, 1 month after the start and then every 3 months, or when indicated. Marked transient and reversible increase in liver transaminases, in most cases, within normal values. If the activity of hepatic transaminases above the norm, it is necessary to reduce the dose or cancel it. It should also determine the concentration of lipids in fasting serum before treatment, 1 month after the start and then every 3 months, or when indicated. Typically, lipid concentrations normalized after dose reduction or discontinuation of the drug, as well as a diet. Should be monitored clinically significant increase in the concentration of triglycerides, as they rise above 800 mg / dL or 9 mmol / l may be associated with development of acute pancreatitis, possibly fatal. When the counter hypertriglyceridemia or symptoms of pancreatitis andriol side effects should be discontinued. In rare cases, patients treated , described depression, psychotic symptoms, and very rarely – suicide attempts and suicide. Although their causal relationship to the use of the drug has not been established, you must take special care in patients with a history of depression and observe all patients on the subject of depression in the course of drug treatment, referring them to a specialist andriol tc if necessary. However, the abolition may not result in the disappearance of symptoms and may need further observation and treatment by a specialist. In rare cases at the beginning of therapy, there was aggravation of acne, which is held for 7-10 days with no dose adjustment of medication. buy legal anabolic steroids online
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